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CAS Number 144-48-9

Linear Formula ICH2CONH2

Molecular Weight 184.96

Beilstein/REAXYS Number 1739080

EC Number 205-630-1

MDL number MFCD00008028

PubChem Substance ID 24278486

NACRES NA.77

Description

Packaging

5, 25, 100 g in glass bottle

Application

Alkylating reagent for cysteine residues in peptide sequencing. By virtue of reaction with cysteine, it is an irreversible inhibitor of enzymes with cysteine at the active site. It reacts much more slowly with histidine residues, but that activity is responsible for inhibition of ribonuclease.

Features and Benefits

This compound is also offered as part of Sigma′s Library of Pharmacologically Active Compounds (LOPAC®1280), a biologically annotated collection of high-quality, ready-to-screen compounds. Click here to learn more.

Legal Information

LOPAC is a registered trademark of Sigma-Aldrich Co. LLC

Properties

Related Categories
A to C, Biochemicals and Reagents, Carnitine acetyltransferase, Core Bioreagents, D to K,

Enzyme Inhibitors, Enzyme Inhibitors by Enzyme, Enzymes, Inhibitors, and Substrates, Galactose oxidase, General Reagents, Life Science Reagents for Protein Electrophoresis, Life Science Reagents for Protein Expression and Purification, P to Q, Phosphogluconic dehydrogenase, 6-, Research Essentials

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Quality Level 300
biological source synthetic (organic)
product line BioUltra
assay ≥99% (NMR)
form powder
impurities ≤0.0005% Phosphorus (P)
≤0.1% Insoluble matter
mp 92-95 °C (lit.)
solubility H2O: 0.5 M, clear, colorless
anion traces chloride (Cl): ≤0.05%
sulfate (SO42-): ≤0.05%
cation traces Al: ≤0.0005%
Ca: ≤0.0005%
Cu: ≤0.0005%
Fe: ≤0.0005%
K: ≤0.005%
Mg: ≤0.0005%
NH4+: ≤0.05%
Na: ≤0.05%
Pb: ≤0.001%
Zn: ≤0.0005%
storage temp. 2-8°C
SMILES string NC(=O)CI
InChI 1S/C2H4INO/c3-1-2(4)5/h1H2,(H2,4,5)
InChI key PGLTVOMIXTUURA-UHFFFAOYSA-N
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