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Synonyms: Oxalic acid diethyl ester

PROPERTIES

Quality Level 100

biological source synthetic

assay ≥98.0% (On Dried Basis)

form powder

color white to off-white

mp 147 °C (dec.) (lit.)

Mode of action cell wall synthesis | interferes

antibiotic activity spectrum Gram-negative bacteria

Gram-positive bacteria mycobacteria

storage temp. −20°C

SMILES string N[C@@H]1CONC1=O

DESCRIPTION

General description

Chemical structure: amino acid derivatives

Application

D-Cycloserine acts as inhibitor of various enzymes.

Biochem/physiol Actions

Mode of Action: Inhibits cell wall biosynthesis (D-Ala peptide bond formation). Also prevents conversion of D-Ala to L-Ala. Bacteriostatic. Mode of Resistance: D-Ala transport interference.
Mode of Action: Inhibits cell wall biosynthesis (D-Ala peptide bond formation). Also prevents conversion of D-Ala to L-Ala. Bacteriostatic.
Partial agonist at the glycine modulatory site of NMDA glutamatergic receptors; antibiotic against Gram-negative bacteria.
Mode of Resistance: D-Ala transport interference.
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